The mission of the CRG is to discover and advance knowledge for the benefit of society, public health and economic prosperity.
The main research interest of the Comparative Genomics Group is to understand the complex relationships between genome sequences and phenotypes and how these two features evolve across species. The group generally uses large-scale phylogenetics approaches that allow looking at the evolution of genomes from the perspective of all of their genes, and the group applies these analyses to a variety of biological questions related the evolution and function of organelles, pathways, and protein families. The Comparative Genomics Group has a special interest in understanding processes related to human pathogenesis (emergence of infectious disease, and organelle-related genetic diseases).
Through collaborations with experimental groups comparative genomics are applied to discover new mechanisms and genes involved in interesting processes, especially those of clinical relevance (see lines of research). Given that the Comparative Genomics Group works in an emerging field and is exposed to new types and scales of data.