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Bernhard Hube

Project Partner
Microbial Pathogenicity Mechanisms
+49 3641 532-1401
Beutenbergstraße 11a
07745 Jena
Germany

Research Interests: Molecular biology of human pathogenic fungi (Candida albicans, C. glabrata); functional genomics; host/pathogen interactions; infection models; infection associated genes; metal aquisition; intracellular survival; invasion mechanisms; microevolution; morphology, mode of action of antifungal agents

 

Education and Scientific Career

Since 2007      Head of Department at HKI, Jena

Since 2006      Professor Microbial Pathogenicity at Friedrich Schiller University Jena

2005 – 2006    Head of Division “Mycology”, Robert Koch Institute Berlin

2000 – 2005    Group Leader of independent research group, Robert Koch Institute Berlin

2000 – 2006    Lecturer for Microbiology, Free University Berlin

1996 – 2000    Assistant Professor, University Hamburg

1995 – 1996    Postdoc, University Hamburg

1992 – 1995    Honour Research Fellow, University Aberdeen

1991 – 1992    Postdoc, University Goettingen

1987 – 1991    PhD, University Goettingen

1986                Diploma in Microbiology, University Goettingen

 

Awards – Appointments – Scientific Activities

Coordinator "FunComPath" consortium – steering committee ZIK Septomics, SFB/Transregio FungiNet and Program Committee ASM Candida and candidiasis – Associated Editor/Editorial Board Cellular Microbiology, mBio, FEMS Yeast Research – AAM Fellow – PI in four DFG projects, ILRS, JSMC – Main awards from DGHM, DMYKG, Seliger-Stiftung – Honorary member DMykG – Co-Organizer FEBS advanced practical course 2016 – Scientific Advisory Board Wellcome Trust Strategic Award (Aberdeen)

 

Institution
Supervised projects
This ESR's goal will be to identify markers and transcriptional profiles common to fungal infection, and specific to C. albicans and C. glabrata infection.
This ESR's goal will be to identify virulence factors up-regulated in C. albicans and the host, as compared to uninfected women with normal vaginal microflora. Candidate genes will be developed into prototype diagnostic tools.
This ESR's goal will be to increase the understanding of how host-pathogen interactions vary during infection and across Candida species by comparative transcriptome approaches.
This ESR's goal will be to identify markers and transcriptional profiles common to fungal infection, and specific to C. parapsilosis infection.
This ESR's goal will be to identify markers and transcriptional profiles common to fungal infection, and specific to C. tropicalis infection.
This ESR's goal will be to identify antifungal resistance biomarkers in main pathogenic Candida species and the isolation and assessment of llama antibodies against selected candidate biomarkers.
Location